Lack of efficacy for fluoxetine in PTSD: a placebo controlled trial in combat veterans.


BACKGROUND Fluoxetine and placebo were studied in a population of combat veterans with severe, chronic PTSD. METHODS Twelve male veterans with PTSD were enrolled in a 12 week double-blind evaluation of fluoxetine and placebo. Mean fluoxetine dose at endpoint (week 12) was 48 mg/day with a range of 10 mg to 60 mg. RESULTS One fluoxetine patient responded… (More)


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