Lack of effect of exogenous insulin-like growth factor-I (IGF-I) on chick embryo growth rate.

@article{Spencer1990LackOE,
  title={Lack of effect of exogenous insulin-like growth factor-I (IGF-I) on chick embryo growth rate.},
  author={G. S. G. Spencer and G. J. Garssen and A R Gerrits and E. Martin Spencer and Steve C. Kestin},
  journal={Reproduction, nutrition, development},
  year={1990},
  volume={30 4},
  pages={515-21}
}
Direct evidence that IGF-I has any significant effect on embryo growth is lacking. We therefore studied the effect of administration of IGF-I on the chick embryo in ovo. Five hundred ng pure IGF-I (purified from human plasma) were given to chick embryos on 2 occasions (7 and 14 d) by injection directly into the allantoic sac. Treated and control (saline… CONTINUE READING