Lack of direct role for calcium in ischemic diastolic dysfunction in isolated hearts.

@article{Eberli2000LackOD,
  title={Lack of direct role for calcium in ischemic diastolic dysfunction in isolated hearts.},
  author={Franz Robert Eberli and Hinrik Str{\"o}mer and M. C. Ferrell and Niraj Varma and James Plunkett Morgan and Stefan Neubauer and Carl S. Apstein},
  journal={Circulation},
  year={2000},
  volume={102 21},
  pages={2643-9}
}
BACKGROUND Ischemia is characterized by an increase in intracellular calcium and occurrence of diastolic dysfunction. We investigated whether the myocyte calcium level is an important direct determinant of ischemic diastolic dysfunction. METHODS AND RESULTS We exposed isolated, perfused isovolumic (balloon in left ventricle) rat and rabbit hearts to low… CONTINUE READING