Lack of cortical contrast gain control in human photosensitive epilepsy

@article{Porciatti2000LackOC,
  title={Lack of cortical contrast gain control in human photosensitive epilepsy},
  author={Vittorio Porciatti and Paolo Bonanni and Adriana Fiorentini and Renzo Guerrini},
  journal={Nature Neuroscience},
  year={2000},
  volume={3},
  pages={259-263}
}
Television and video games may be powerful triggers for visually induced epileptic seizures. To better understand the triggering elements of visual stimuli and cortical mechanisms of hyperexcitability, we examined eleven patients with idiopathic photosensitive epilepsy by recording visually evoked potentials (VEPs) in response to temporally modulated patterns of different contrast. For stimuli of low–medium, but not high, temporal frequency, the contrast dependence of VEP amplitude and latency… CONTINUE READING