Lack of correlation between objective response and death rate in multiple myeloma patients treated with oral melphalan and prednisone.

@article{Marmont1991LackOC,
  title={Lack of correlation between objective response and death rate in multiple myeloma patients treated with oral melphalan and prednisone.},
  author={Filippo Marmont and Alessandro Levis and Michele Falda and Luigi Resegotti},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={1991},
  volume={2 3},
  pages={191-5}
}
An analysis of survival by response category was performed on 76 patients with stage II and III multiple myeloma, who were treated with oral melphalan and prednisone. The analysis demonstrated a survival advantage for responders over non-responders only in stage III patients (32.3 months for responders vs. 15.6 months for non-responders, p = 0.03). However, two possible sources of error must be considered: a) the poor prognosis of early responders that may adversely affect the survival of all… CONTINUE READING