Lack of correlation between early intracellular calcium ion rises and the onset of apoptosis in thymocytes.

@article{Beaver1994LackOC,
  title={Lack of correlation between early intracellular calcium ion rises and the onset of apoptosis in thymocytes.},
  author={Julie Beaver and Patrick L. Waring},
  journal={Immunology and cell biology},
  year={1994},
  volume={72 6},
  pages={
          489-99
        }
}
Apoptosis, a well-recognized process of cell death, is usually defined by chromatin condensation, plasma membrane blebbing, reduction in cell volume, and in many cell types the cleavage of DNA into nucleosomal multiples, and finally the formation of apoptotic bodies. We have characterized the time of onset and the range of concentrations at which the toxins gliotoxin and thapsigargin induce apoptosis in thymocytes. We also looked for early changes in cytosolic calcium ion concentration ([Ca2+]i… CONTINUE READING
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