Lack of complementation between xeroderma pigmentosum complementation groups D and H

@article{Johnson1989LackOC,
  title={Lack of complementation between xeroderma pigmentosum complementation groups D and H},
  author={Robert T. Johnson and George C. Elliott and Shoshana Squires and Valerie C. Joysey},
  journal={Human Genetics},
  year={1989},
  volume={81},
  pages={203-210}
}
The construction of permanent hybrid cell lines between xeroderma pigmentosum (XP) cells from different complementation groups allows analysis not only of the degree of repair correction but also of the restoration of biological activity to the UV-irradiated cells. With use of an immortal human cell line (HD2) that expresses excision repair defects typical of XP group D, a series of permanent hybrid cells has been produced with XP cells from groups A to H. Excision repair, as measured by… CONTINUE READING