Lack of clinically significant gross structural abnormalities in MRIs of older patients with schizophrenia and related psychoses.

@article{Symonds1997LackOC,
  title={Lack of clinically significant gross structural abnormalities in MRIs of older patients with schizophrenia and related psychoses.},
  author={Laura L. Symonds and John M. Olichney and Terry L. Jernigan and Jody Corey-Bloom and John F. Healy and Dilip V. Jeste},
  journal={The Journal of neuropsychiatry and clinical neurosciences},
  year={1997},
  volume={9 2},
  pages={251-8}
}
The authors examined the reports of MRI brain studies of 69 patients with DSM-III-R-diagnosed psychotic disorders (30 early-onset and 24 late-onset schizophrenia patients and 15 with other psychoses) and 41 normal comparison subjects. Participants' ages ranged from 45 to 87 years. A qualitative rating scheme determined type and severity of clinically detectable abnormalities, including volume loss, infarcts, lacunae, and white matter hyperintensities. In this clinically well-characterized… CONTINUE READING
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