Lack of change in microRNA expression in adult mouse liver following treatment with benzo(a)pyrene despite robust mRNA transcriptional response.

Abstract

Benzo(a)pyrene (BaP) is a mutagenic and carcinogenic environmental contaminant. Metabolic activation of BaP is required for it to exert its mutagenic effects. Metabolism occurs via BaP interaction with the aryl hydrocarbon receptor (AHR) resulting in induction of phase 1 enzymes. Exposure to BaP is expected to cause differential regulation of AHR-responsive… (More)
DOI: 10.1016/j.mrgentox.2010.02.012

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Cite this paper

@article{Yauk2011LackOC, title={Lack of change in microRNA expression in adult mouse liver following treatment with benzo(a)pyrene despite robust mRNA transcriptional response.}, author={Carole Lyn Yauk and Kelly E Jackson and Morie Malowany and Andrew Williams}, journal={Mutation research}, year={2011}, volume={722 2}, pages={131-9} }