Lack of benefit of laxatives as adjunctive therapy for functional nonretentive fecal soiling in children.

@article{Ginkel2000LackOB,
  title={Lack of benefit of laxatives as adjunctive therapy for functional nonretentive fecal soiling in children.},
  author={Rijk van Ginkel and Marc Alexander Benninga and Pietjan E Blommaart and R. N. van der Plas and Guy E. E. Boeckxstaens and Hans A. B{\"u}ller and Jan Ajm Taminiau},
  journal={The Journal of pediatrics},
  year={2000},
  volume={137 6},
  pages={
          808-13
        }
}
OBJECTIVES To determine whether the combination of laxative treatment and biofeedback therapy (BF) is more effective for management of functional nonretentive fecal soiling than biofeedback therapy alone. STUDY DESIGN In a prospective nonblinded study, 48 children were randomized in 2 groups: treatment with oral laxatives (LAX) and 5 sessions of BF (BF + LAX) or 5 sessions of BF alone (BF) during a treatment intervention period of 7 weeks. Biofeedback was performed with perfused manometry… CONTINUE READING

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