Lack of association of the VEGF gene promoter (−634 G→C and −460 C→T) polymorphism and the risk of advanced retinopathy of prematurity

@article{Shastry2006LackOA,
  title={Lack of association of the VEGF gene promoter (−634 G→C and −460 C→T) polymorphism and the risk of advanced retinopathy of prematurity},
  author={Barkur S. Shastry and Xianggui Qu},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2006},
  volume={245},
  pages={741-743}
}
Recently, it has been reported that genetic polymorphism (−634 G→C and −460 C→T) in the promoter region of the vascular endothelial growth factor (VEGF) gene can influence the progression of retinopathy of prematurity (ROP). In order to evaluate its general applicability as a screening procedure in clinics and to replicate the above result, we have undertaken the following study. We have analyzed a cohort of 61 patients with advanced ROP (stage 4 and 5) along with 61 normal controls for the… CONTINUE READING