Lack of association of polymorphisms of the angiotensin converting enzyme and angiotensinogen genes with nonfamilial hypertrophic or dilated cardiomyopathy.

@article{Yamada1997LackOA,
  title={Lack of association of polymorphisms of the angiotensin converting enzyme and angiotensinogen genes with nonfamilial hypertrophic or dilated cardiomyopathy.},
  author={Yasukazu Yamada and Sahoko Ichihara and Taku Fujimura and Mitsuhiro Yokota},
  journal={American journal of hypertension},
  year={1997},
  volume={10 8},
  pages={921-8}
}
Although several genes or genetic loci that are either responsible for or confer susceptibility to familial hypertrophic cardiomyopathy (HCM) or dilated cardiomyopathy (DCM) have been identified, genetic defects that underlie nonfamilial HCM or DCM remain to be characterized. An allelic association study for the angiotensin converting enzyme (ACE) and angiotensinogen genes has now been performed with 71 patients with nonfamilial HCM, 88 patients with nonfamilial DCM, and 122 healthy control… CONTINUE READING

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Angiotensinconverting enzyme gene polymorphism in Japanese patients with hypertrophic cardiomyopathy

  • K Yoneda, H Okamoto, M Machida
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