Lack of association of VEGF promoter polymorphisms with sporadic ALS.

@article{Chen2006LackOA,
  title={Lack of association of VEGF promoter polymorphisms with sporadic ALS.},
  author={Wenjie Chen and Mohammad Saeed and Hailei Mao and Nailah Siddique and Lisa M. Dellefave and W Y Hung and H X Deng and Robert L. Sufit and Scott L Heller and Jonathan L. Haines and Margaret A. Pericak-Vance and Teepu Siddique},
  journal={Neurology},
  year={2006},
  volume={67 3},
  pages={508-10}
}
The authors tested the association of three vascular endothelial growth factor (VEGF) promoter polymorphisms with sporadic ALS (SALS) to verify the results of a previous study and to investigate their modifier effects on the subphenotypes of SALS in a large family-based and case-control cohort of North American white subjects (N = 1,603). They did not find any association of the VEGF promoter polymorphisms with SALS or its subphenotypes, suggesting that they do not have a direct causal role in… CONTINUE READING