Lack of association of SDF-1 3'A variant allele with long-term nonprogressive HIV-1 infection is extended beyond 16 years.

@article{Vidal2005LackOA,
  title={Lack of association of SDF-1 3'A variant allele with long-term nonprogressive HIV-1 infection is extended beyond 16 years.},
  author={F. Javier S{\'a}nchez Vidal and Joaquim Peraire and Pere Domingo and Montserrat Broch and Hernando Knobel and Enric Pedrol and David Dalmau and Consuelo Vilad{\'e}s and Ma Ant{\`o}nia Sambeat and Cristina Guti{\'e}rrez and Crist{\'o}bal Richart},
  journal={Journal of acquired immune deficiency syndromes},
  year={2005},
  volume={40 3},
  pages={276-9}
}
We studied the frequency of the SDF-1 3'A allelic variant (801G-->A) in a cohort of white Spaniards made up of (1) HIV-1-infected long-term nonprogressors (LTNPs) older than 16 years of age (n = 57), (2) HIV-1-infected usual progressors (UPs; n = 107), and (3) a group of healthy controls (n = 100). The mutant SDF-1 3'A allele was observed in 28% of LTNPs, 19% of UPs, and 26% of healthy controls (P = not significant). Homozygosity for the 3'A mutation was detected in 7%, 4%, and 3% of LTNPs, UPs… CONTINUE READING