Lack of association of HLA-DRB1 genotype with radiologic progression in Japanese patients with early rheumatoid arthritis.

@article{Higami1997LackOA,
  title={Lack of association of HLA-DRB1 genotype with radiologic progression in Japanese patients with early rheumatoid arthritis.},
  author={Kenshi Higami and Masayuki Hakoda and Yuko Matsuda and Haruo Ueda and Sadao Kashiwazaki},
  journal={Arthritis and rheumatism},
  year={1997},
  volume={40 12},
  pages={2241-7}
}
OBJECTIVE To evaluate the role of HLA-DRB1 genotypes in the development and progression of the rheumatoid arthritis (RA) disease process. METHODS Patients with polyarthritis of < 1 year in duration were consecutively enrolled in the study. Other inclusion criteria were no diagnosis of inflammatory diseases other than RA, and no history of taking disease-modifying antirheumatic drugs or steroids. Patients were evaluated every 4 weeks, and radiographs of the hands/wrists and feet were taken at… CONTINUE READING