Lack of association of CCR2-64I and CCR5-Delta 32 with type 1 diabetes and latent autoimmune diabetes in adults.

@article{Gambelunghe2003LackOA,
  title={Lack of association of CCR2-64I and CCR5-Delta 32 with type 1 diabetes and latent autoimmune diabetes in adults.},
  author={Giovanni Gambelunghe and Mehran Ghaderi and Annalisa Brozzetti and Paola Del Sindaco and Babeck Gharizadeh and Paul E. Nyren and Peter Hjelmstr{\"o}m and Liene Nikitina-Zake and Carani Balaraman Sanjeevi and Alberto Falorni},
  journal={Human immunology},
  year={2003},
  volume={64 6},
  pages={629-32}
}
It is well known that type 1 diabetes mellitus (T1DM) is a complex genetic disease resulting from the autoimmune destruction of pancreatic beta cells. Several genes have been associated with susceptibility and/or protection for T1DM, but the disease risk is mostly influenced by genes located in the class II region of the major histocompatibility complex. The attraction of leukocytes to tissues is essential for inflammation and the beginning of autoimmune reaction. The process is controlled by… CONTINUE READING