Lack of association between the interleukin-1 gene complex and schizophrenia in a Japanese population.

@article{Watanabe2007LackOA,
  title={Lack of association between the interleukin-1 gene complex and schizophrenia in a Japanese population.},
  author={Yuichiro Watanabe and Ayako Nunokawa and Naoshi Kaneko and Tatsuyuki Muratake and Masataka Koizumi and Toshiyuki Someya},
  journal={Psychiatry and clinical neurosciences},
  year={2007},
  volume={61 4},
  pages={
          364-9
        }
}
Interleukin-1 (IL1) is an inflammatory cytokine and exerts neurodegenerative effects in the brain. Several studies have indicated that IL1 is likely to be involved in the pathogenesis of schizophrenia. Recent genetic studies have revealed that the IL1 gene complex (IL,1 alpha, IL1, beta and IL1 receptor antagonist) was associated with schizophrenia, although contradictory findings have also been reported. To assess whether the IL1 gene complex was implicated in vulnerability to schizophrenia… CONTINUE READING

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