Lack of association between the brain-derived neurotrophin factor (C-270T) polymorphism and late-onset Alzheimer’s disease (LOAD) in Brazilian patients

@article{Nishimura2004LackOA,
  title={Lack of association between the brain-derived neurotrophin factor (C-270T) polymorphism and late-onset Alzheimer’s disease (LOAD) in Brazilian patients},
  author={Agnes Lumi Nishimura and Jo{\~a}o Ricardo M. Oliveira and Miguel Mitne-Neto and Camila Santa Cruz Guindalini and Richardo Nitrini and Val{\'e}ria Santoro Bahia and Paulo Roberto de Brito-Marques and Paulo A Otto and Mayana Zatz},
  journal={Journal of Molecular Neuroscience},
  year={2004},
  volume={22},
  pages={257-260}
}
After the identification of the apolipoprotein E gene isoform (APOE-ε4) as a risk factor for late-onset Alzheimer’s disease (LOAD), the search for other polymorphisms associated with AD has been undertaken by many groups of investigators around the world. These studies have shown controversial results in many populations. More recently, a single nucleotide… CONTINUE READING