Lack of association between the TNF alpha G -308 A promoter polymorphism and periodontal disease.

@article{Folwaczny2004LackOA,
  title={Lack of association between the TNF alpha G -308 A promoter polymorphism and periodontal disease.},
  author={Matthias Folwaczny and J{\"u}rgen Glas and Helga-Paula T{\"o}r{\"o}k and Monika Mende and Christian Folwaczny},
  journal={Journal of clinical periodontology},
  year={2004},
  volume={31 6},
  pages={449-53}
}
BACKGROUND Immunorelevant gene polymorphisms might influence the susceptibility for periodontal disease. The present study assessed the frequency of a promoter polymorphism (-308G-to-A) of the tumour necrosis factor (TNF)alpha gene in patients with periodontitis and controls. METHODS Eighty-one patients with generalized chronic periodontitis and 80 healthy controls were genotyped for the -308 polymorphism of the TNF alpha gene by PCR amplification and subsequent restriction fragment length… CONTINUE READING