Lack of association between the -759C/T polymorphism of the 5-HT2C receptor gene and olanzapine-induced weight gain among Korean schizophrenic patients.

@article{Park2008LackOA,
  title={Lack of association between the -759C/T polymorphism of the 5-HT2C receptor gene and olanzapine-induced weight gain among Korean schizophrenic patients.},
  author={Y-M Park and J-H Cho and S-G Kang and Je Choi and S-H Lee and Leen Kim and H-J Lee},
  journal={Journal of clinical pharmacy and therapeutics},
  year={2008},
  volume={33 1},
  pages={
          55-60
        }
}
BACKGROUND Weight gain can be an adverse effect of antipsychotics that significantly affects long-term health and treatment compliance. Many reports have suggested that the 5-HT2C receptor gene (HTR2C) is related to appetite and eating behaviours associated with body weight change. We hypothesized that there was a relationship between the HTR2C -759C/T polymorphism and olanzapine-induced weight gain. METHOD Seventy-nine Korean schizophrenic patients were examined. Their weight was measured… CONTINUE READING

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HTR2C polymorphisms, olanzapine-induced weight gain and antipsychotic-induced metabolic syndrome in schizophrenia patients: a meta-analysis.

  • International journal of psychiatry in clinical practice
  • 2014
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CITES BACKGROUND, RESULTS & METHODS
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