Lack of association between the –260 C→T promoter polymorphism of the endotoxin receptor CD14 gene and the CD14 density of unstimulated human monocytes and soluble CD14 plasma levels

Abstract

Objective: CD14 is a receptor for endotoxin and binds components of Gram-positive and Gram-negative bacteria. CD14-bearing monocytes respond to stimulation with the increased synthesis and release of cytokines. The recently described –260 C→T promoter polymorphism of the CD14 gene has been found to be related to a risk of myocardial infarction. This study… (More)
DOI: 10.1007/s001340101106

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