Lack of association between polymorphisms from genome-wide association studies and tuberculosis in the Chinese population.

@article{Ji2013LackOA,
  title={Lack of association between polymorphisms from genome-wide association studies and tuberculosis in the Chinese population.},
  author={Lin-Dan Ji and Peng-fei Chai and Bi-Bo Zhou and Nelson L. S. Tang and Wen-hua Xing and Fang Yuan and Li-juan Fei and Li-Na Zhang and Jin Xu},
  journal={Scandinavian journal of infectious diseases},
  year={2013},
  volume={45 4},
  pages={
          310-4
        }
}
Genome-wide association studies (GWAS) have identified rs4331426 and rs2057178 as being associated with tuberculosis (TB) in African populations. Both are common single nucleotide polymorphisms (SNPs) in Africans, but they are much rarer in Eurasian populations. In order to corroborate these results, we carried out a case-control study in the Chinese population; these 2 SNPs were genotyped in 600 pulmonary TB patients and 618 healthy controls. The results showed that neither of the SNPs was… CONTINUE READING
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Genetic variants at 18q11.2 and 8q24 identified by genome-wide association studies were not associated with pulmonary tuberculosis risk in Chinese population.

  • Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
  • 2016
VIEW 3 EXCERPTS
CITES RESULTS
HIGHLY INFLUENCED

Association of rs4331426 and rs2057178 with Risk of Tuberculosis: Evidence from a Meta-Analysis.

  • Genetic testing and molecular biomarkers
  • 2016
VIEW 2 EXCERPTS
CITES BACKGROUND

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