Lack of association between let-7 binding site polymorphism rs712 and risk of nasopharyngeal carcinoma

Abstract

Nasopharyngeal carcinoma (NPC) is characterized by its highly invasive and metastatic features. Therefore, screening genetic biomarkers of NPC to achieve early diagnose would be of great value for NPC therapy. Single nucleotide polymorphisms in let-7 miRNA binding site in 3′ untranslated region of KRAS mRNA have been found to be associated with various… (More)
DOI: 10.1007/s10689-013-9681-4

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