Lack of association between cytokine gene polymorphisms and silicosis and pulmonary tuberculosis in Chinese iron miners.

@article{Wu2008LackOA,
  title={Lack of association between cytokine gene polymorphisms and silicosis and pulmonary tuberculosis in Chinese iron miners.},
  author={Fen Wu and Yabin Qu and Yunxia Tang and Duozhi Cao and Pin Sun and Zhao-lin Xia},
  journal={Journal of occupational health},
  year={2008},
  volume={50 6},
  pages={445-54}
}
Silicosis is a fibrotic lung disease produced by the inhalation and deposition of silica dust. The association between silicosis and pulmonary tuberculosis (PTB) has been well established. Cytokines participate in the development and progression of silicosis and PTB. Functional polymorphisms in cytokine genes have been identified that alter cytokine production. The aims of the current investigation were to determine whether functional polymorphisms in the tumor necrosis factor-alpha (TNF-alpha… CONTINUE READING

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