Lack of association between STAT4 gene polymorphism and biopsy-proven giant cell arteritis.

@article{PalominoMorales2009LackOA,
  title={Lack of association between STAT4 gene polymorphism and biopsy-proven giant cell arteritis.},
  author={Rogelio Jesus Palomino-Morales and Tom{\'a}s Ram{\'o}n V{\'a}zquez-Rodr{\'i}guez and Inmaculada C. Morado and Santos Casta{\~n}eda and Norb{\'e}rto Ortego-Centeno and Jos{\'e} Alberto Miranda-Filloy and Jos{\'e} R. Lamas and Javier Mart{\'i}n and Miguel A Gonz{\'a}lez-Gay},
  journal={The Journal of rheumatology},
  year={2009},
  volume={36 5},
  pages={
          1021-5
        }
}
OBJECTIVE To investigate the potential implication of the STAT4 gene polymorphism rs7574865 in the predisposition to or the clinical expression of giant cell arteritis (GCA). METHODS A total of 212 patients diagnosed with biopsy-proven GCA were studied. DNA from patients and controls matched by age, sex, and ethnicity was obtained from peripheral blood. Samples were genotyped for STAT4 rs7574865 polymorphism. RESULTS No statistically significant differences in the allele frequencies for the… CONTINUE READING

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