Lack of association between HoxA1 and HoxB1 gene variants and autism in 110 multiplex families.

@article{Li2002LackOA,
  title={Lack of association between HoxA1 and HoxB1 gene variants and autism in 110 multiplex families.},
  author={Jun Z. Li and Holly K Tabor and Loan Nguyen and Christopher Scott Gleason and Linda J Lotspeich and Donna Spiker and Neil J. Risch and Richard M. Myers},
  journal={American journal of medical genetics},
  year={2002},
  volume={114 1},
  pages={24-30}
}
A recent report suggested that the HoxA1 and/or HoxB1 genes play a role in susceptibility to autism. To determine whether these findings could be confirmed, we screened these genes for DNA polymorphisms by sequencing all exons in 24 individuals with autism. We identified the same sequence variants in the genes that appeared in this report, which include one single-base substitution variant in HoxA1 and a common haplotype in HoxB1. We performed an association study by applying the transmission… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…