Lack of antiviral effect of a short course of mycophenolate mofetil in patients with chronic hepatitis C virus infection

@article{Firpi2003LackOA,
  title={Lack of antiviral effect of a short course of mycophenolate mofetil in patients with chronic hepatitis C virus infection},
  author={R. Firpi and D. Nelson and G. Davis},
  journal={Liver Transplantation},
  year={2003},
  volume={9}
}
Mycophenolate mofetil (MMF) is an immunosuppressive agent that is widely used in the management of liver transplant recipients. MMF inhibits the inosine monophosphate dehydrogenase that has been shown to have in vitro antiviral properties against flaviviruses, suggesting the possibility that it might also inhibit the hepatitis C virus (HCV). The goal of this short‐term dose escalation study was to assess the antiviral effects of MMF on HCV replication. Patients with chronic hepatitis C who had… Expand
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