Lack of antioxidative properties of vitamin C and pyruvate in cultured retinal pigment epithelial cells

@article{Zeitz2006LackOA,
  title={Lack of antioxidative properties of vitamin C and pyruvate in cultured retinal pigment epithelial cells},
  author={Oliver Zeitz and Lars Schlichting and Gisbert Richard and Olaf Strauss},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2006},
  volume={245},
  pages={276-281}
}
Oxidative damage to the retinal pigment epithelium might be involved in the pathogenesis of age related macular degeneration. Thus antioxidative protection represents a rationale for a causative therapy or prophylaxis. The aim of the present study is to evaluate antioxidative properties of vitamin C and pyruvate at retinal pigment epithelial (RPE) cells exposed to oxidative stress. The ability of vitamin C and pyruvate to quench hydroxyl radicals was tested using the di-hydro-rhodamine (DHR… CONTINUE READING

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