Lack of angiotensin I accumulation after converting enzyme blockade by enalapril or lisinopril in man.

@article{Nussberger1987LackOA,
  title={Lack of angiotensin I accumulation after converting enzyme blockade by enalapril or lisinopril in man.},
  author={Juerg Nussberger and D. B. Brunner and Bernard Waeber and J{\'e}r{\^o}me Biollaz and Hans Rudolf Brunner},
  journal={Clinical science},
  year={1987},
  volume={72 3},
  pages={387-9}
}
In nine normal volunteers, a series of five venous blood samples was obtained before and up to 24 h after converting enzyme inhibition by a single oral dose of enalapril or lisinopril. Plasma renin activity and blood angiotensin I were measured. A close linear relationship was found between the increase in plasma renin activity and the increase in blood angiotensin I. The linear correlation between plasma renin activity and blood angiotensin I remained after converting enzyme inhibition. Thus… CONTINUE READING