Lack of an association between the presence of tumor necrosis factor or interleukin-1 alpha in the blood and weight loss among elderly patients.

@article{Mooradian1990LackOA,
  title={Lack of an association between the presence of tumor necrosis factor or interleukin-1 alpha in the blood and weight loss among elderly patients.},
  author={Arshag D Mooradian and Richard L Reed and Dan Osterweil and N. Scott Clements and Philip E Scuderi},
  journal={Journal of the American Geriatrics Society},
  year={1990},
  volume={38 4},
  pages={397-401}
}
To determine the association between blood cytokine levels and body weight loss in elderly patients, serum levels of cachectin/tumor necrosis factor alpha (TNF) and interleukin-1 alpha (IL-1) were measured with specific and sensitive ELISA systems. Of the 19 healthy young subjects, two (10.5%) had detectable levels of serum TNF and one (5.3%) was positive for IL-1. In the healthy elderly group, two of the 12 subjects (16.7%) had measurable TNF levels and four (33.3%) had elevated IL-1 levels… CONTINUE READING

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