Lack of Salt-Inducible Kinase 2 (SIK2) Prevents the Development of Cardiac Hypertrophy in Response to Chronic High-Salt Intake

@inproceedings{Popov2014LackOS,
  title={Lack of Salt-Inducible Kinase 2 (SIK2) Prevents the Development of Cardiac Hypertrophy in Response to Chronic High-Salt Intake},
  author={Sergej Popov and Hiroshi Takemori and Takeshi Tokudome and Yuanjie Mao and Kentaro Otani and Naoki Mochizuki and Nuno Miguel Pires and Maria Jo{\~a}o Pinho and Anders Franco-Cereceda and Lucia Torielli and Mara Ferrandi and Anders Hamsten and Patr{\'i}cio Soares-da-Silva and Per Eriksson and Alejandro Mario Bertorello and Laura Brion},
  booktitle={PloS one},
  year={2014}
}
Cardiac left ventricle hypertrophy (LVH) constitutes a major risk factor for heart failure. Although LVH is most commonly caused by chronic elevation in arterial blood pressure, reduction of blood pressure to normal levels does not always result in regression of LVH, suggesting that additional factors contribute to the development of this pathology. We… CONTINUE READING