Lack of PTEN expression in endometrial intraepithelial neoplasia is correlated with cancer progression.

@article{Baak2005LackOP,
  title={Lack of PTEN expression in endometrial intraepithelial neoplasia is correlated with cancer progression.},
  author={Jan Pieter Albert Baak and Bianca van Diermen and Anita Steinbakk and Emiel A. M. Janssen and Ivar Skaland and George L. Mutter and Bent E Fiane and Kjell I. L\ovslett},
  journal={Human pathology},
  year={2005},
  volume={36 5},
  pages={555-61}
}
We tested the hypothesis that PTEN inactivation may stratify cancer progression risk among putative endometrial hyperplasias, classified prognostically by means of the morphometric D score (DS). The DS, calculated from 3 morphometric variables measured in routine hematoxylin-eosin-stained endometrial biopsy slides, is the most sensitive and specific method of endometrial cancer risk prediction currently available. Clinical outcomes of 103 women with endometrial hyperplasia on biopsy were… CONTINUE READING
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