Lack of Fas antagonism by Met in human fatty liver disease

Abstract

Hepatocytes in fatty livers are hypersensitive to apoptosis and undergo escalated apoptotic activity via death receptor–mediated pathways, particularly that of Fas-FasL, causing hepatic injury that can eventually proceed to cirrhosis and end-stage liver disease. Here we report that the hepatocyte growth factor receptor, Met, plays an important part in… (More)
DOI: 10.1038/nm1625

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Cite this paper

@article{Zou2007LackOF, title={Lack of Fas antagonism by Met in human fatty liver disease}, author={Chunbin Zou and Jihong Ma and Xue Wang and Lida Guo and Zhenqi Zhu and John Stoops and Amanda E Eaker and C. Jerald Johnson and Stephen S. Strom and George K Michalopoulos and Marie Defrances and Reza Zarnegar}, journal={Nature Medicine}, year={2007}, volume={13}, pages={1078-1085} }