Lack of BRAF(V600E) mutations in giant congenital melanocytic nevi in a Chinese population.

Abstract

Giant congenital melanocytic nevi (CMNs) are at an increased risk for malignant transformation. To explore the mutation frequencies of BRAF(V600E) (V-raf murine sarcoma virus oncogene homolog B1) and NRAS (neuroblastoma ras viral oncogene homolog) codon 61 in CMNs of Chinese, we selected 55 paraffin-embedded tissue blocks, including 37 cases of medium CMNs… (More)
DOI: 10.1097/DAD.0b013e3181fb5bc7

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