Lack of B7 expression, not human leukocyte antigen expression, facilitates immune evasion by human malignant gliomas.

Abstract

OBJECTIVE Lack of human leukocyte antigens and costimulatory molecules have been suggested as mechanisms by which human malignant gliomas avoid immune recognition and elimination. METHODS Using quantitative multiparameter flow cytometric analysis, tumor cells from patients with glioblastoma multiforme (n = 18) were examined ex vivo for the expression of… (More)

Topics

Cite this paper

@article{Anderson2007LackOB, title={Lack of B7 expression, not human leukocyte antigen expression, facilitates immune evasion by human malignant gliomas.}, author={Richard C. E. Anderson and David E Anderson and James Bradley Elder and Melandee D Brown and Christopher E Mandigo and Andrew T. Parsa and Robert R. Goodman and Guy M. McKhann and M B Sisti and Jeffrey N. Bruce}, journal={Neurosurgery}, year={2007}, volume={60 6}, pages={1129-36; discussion 1136} }