Lack of Association between Mannose Binding Lectin and Antibody Responses after Acellular Pertussis Vaccinations

@inproceedings{GrndahlYliHannuksela2014LackOA,
  title={Lack of Association between Mannose Binding Lectin and Antibody Responses after Acellular Pertussis Vaccinations},
  author={Kirsi Gr{\"o}ndahl-Yli-Hannuksela and Juho Vuononvirta and Ville Peltola and Jussi A Mertsola and Qiushui He},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND Mannose-binding lectin (MBL) is one of the key molecules in innate immunity and its role in human vaccine responses is poorly known. This study aimed to investigate the possible association of MBL polymorphisms with antibody production after primary and booster vaccinations with acellular pertussis vaccines in infants and adolescents. METHODOLOGY/PRINCIPAL FINDINGS Five hundred and sixty eight subjects were included in this study. In the adolescent cohort 355 subjects received a… CONTINUE READING

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