Laccase-catalyzed carbon–nitrogen bond formation: coupling and derivatization of unprotected l-phenylalanine with different para-hydroquinones

@article{Hahn2008LaccasecatalyzedCB,
  title={Laccase-catalyzed carbon–nitrogen bond formation: coupling and derivatization of unprotected l-phenylalanine with different para-hydroquinones},
  author={V. Hahn and Annett Mikolasch and Katrin Manda and Dirk Goerdes and Kerstin Thurow and Frieder Schauer},
  journal={Amino Acids},
  year={2008},
  volume={37},
  pages={315-321}
}
Unprotected l-phenylalanine was derivatized by an innovative enzymatic method by means of laccases from Pycnoporus cinnabarinus and Myceliophthora thermophila. During the incubation of l-phenylalanine with para-hydroquinones using laccase as biocatalyst, one or two main products were formed. Dependent on the substitution grade of the hydroquinones mono- and diaminated products were detected. Differences of the used laccases are discussed. The described reactions are of interest for the… CONTINUE READING

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References

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Showing 1-10 of 27 references

Laccase-induced cross-coupling of 4-aminobenzoic acid with para-dihydroxylated compounds 2, 5-dihydroxy-N-(2-hydroxyethyl)-benzamide and 2, 5-dihydroxybenzoic acid methyl ester

  • K Manda, E Hammer, +6 authors JM Bollag
  • J Mol Catal B Enzym
  • 2005
Highly Influential
6 Excerpts

Laccases and phenol oxidases in organic synthesis—a review

  • SG Burton
  • Curr Org Chem
  • 2003
Highly Influential
2 Excerpts

Laccases: a useful group of oxidoreductive enzymes

  • L Gianfreda, F Xu, JM Bollag
  • Bioremediat J
  • 1999
Highly Influential
2 Excerpts

Enzymes catalyzing oxidative coupling reactions of pollutants

  • JM Bollag
  • Metal ions in biological systems,
  • 1992
Highly Influential
2 Excerpts

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