Labyrinthitis, Vestibular Neuritis and Sensorineural Hearing Loss (SNHL)

  title={Labyrinthitis, Vestibular Neuritis and Sensorineural Hearing Loss (SNHL)},
  author={M. A. Naafs},
This mini-review discusses pathogenesis and pathophysiology of vestibular neuritis,labyrinthitis and sensorineural hearing loss (SNHL).In addtion,the role of the immune system as a therapeutic target in the treatment and course of these disorders is evaluated.Viral,bacterial,traumatic. congenital acquired and heriditary causes are discussed. Results of the therapeutic applications of glucosteroid, immunosuppressives and the new biologics are considered. Active target delivery of genetically… Expand
Occupational Diseases in the Petrochemical Sectorand Offshore Upstream Petroleum Industry
Chemicals are used extensively both in industry and in our daily lives. Occupational disease (OD) refers to any disease contracted as a result of exposure to factors arising from work (ILO 2011)-(1).Expand
Labyrinthitis, Vestibular Neuritis and Sensorineural Hearing Loss (SNHL)
This mini-review discusses pathogenesis and pathophysiology of vestibular neuritis, Labyrinthitis and sensorineural hearing loss and active target delivery of genetically modified monocytes seems at present the most attractive option for the treatment of SNHL. Expand


This review focuses on the recent progress in understanding of the aetio-pathogenesis of autoimmune hearing loss along with a description of the various clinical conditions in which they occur. Expand
Vestibular neuronitis. An otoneurological evaluation.
The clinical otoneurological findings of the acute stage included spontaneous nystagmus with Frenzel's glasses and disturbances of the vestibulospinal tests, which improved markedly during the follow-up period and were characteristic of a pure peripheral vestibular disorder. Expand
Viruses and vestibular neuritis: review of human and animal studies.
  • L. Davis
  • Medicine
  • Acta oto-laryngologica. Supplementum
  • 1993
Clinical and serologic studies of patients with vestibular neuritis suggest that the viruses may play a role in the pathogenesis of this disease. Expand
Vestibular neuritis spares the inferior division of the vestibular nerve.
Measurement of the speed and axis of eye rotation during spontaneous nystagmus and the three-dimensional properties of the vestibuloocular reflex suggest that vestibular neuritis is a partial and not a complete unilateral Vestibular lesion and that this partial lesion affects the superior division of thevestibular nerve which includes the afferents from the horizontal and anterior SCCs. Expand
Treatment-Refractory Autoimmune Sensorineural Hearing Loss: Response to Infliximab
The effects of infliximab, a chimeric monoclonal antibody, on hearing in patients with autoimmune sensorineural hearing loss who had previously not responded to steroid therapy and/or treatment with other immunosuppressive drugs such as methotrexate and cyclophosphamide are assessed. Expand
About the pathophysiology of acute unilateral vestibular deficit - vestibular neuritis (VN) or peripheral vestibulopathy (PVP)?
OBJECTIVE To determine whether patients with acute unilateral peripheral vestibulopathy (PVP), often called "vestibular neuritis/neuronitis or neuropathy" (VN) have a vestibular lesion patternExpand
Vertigo: a review of common peripheral and central vestibular disorders.
The focus of this article is the peripheral and central vestibular system, which includes the more common disorders specific to this system, how patients with these disorders present, and management protocols. Expand
Suppurative labyrinthitis associated with otitis media: 26 years' experience.
INTRODUCTION Suppurative labyrinthitis continues to result in significant hearing impairment, despite scientific efforts to improve not only its diagnosis but also its treatment. The definitiveExpand
Immune system of the inner ear as a novel therapeutic target for sensorineural hearing loss
Current understanding of the immune system in the inner ear and its involvement in the pathophysiology of SNHL is addressed, with a focus on the immune mechanism and immunocompetent cells as therapeutic targets. Expand
Clinical efficacy of initial intratympanic steroid treatment on sudden sensorineural hearing loss with diabetes
  • Chi-Sung Han, Jong-Ryul Park, +7 authors H. Lee
  • Medicine
  • Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2009
ITSI is as effective as systemic steroid treatment for sudden SNHL patients with diabetes and it can avoid undesirable side effects and is considered to be a more reasonable alternative as an initial treatment for suddenly SNHL Patients with diabetes. Expand