Laboratory tools for diagnosis and monitoring response in patients with chronic myeloid leukemia.

@article{Tohami2012LaboratoryTF,
  title={Laboratory tools for diagnosis and monitoring response in patients with chronic myeloid leukemia.},
  author={Tali Tohami and Arnon Nagler and Ninette Amariglio},
  journal={The Israel Medical Association journal : IMAJ},
  year={2012},
  volume={14 8},
  pages={501-7}
}
Chronic myeloid leukemia (CML) is a clonal hematological disease that represents 15-20% of all adult leukemia cases. The study and treatment of CML has contributed pivotal advances to translational medicine and cancer therapy. The discovery that a single chromosomal abnormality, the Philadelphia (Ph) chromosome, is responsible for the etiology of this disease was a milestone for treating and understanding CML. Subsequently, CML became the first disease for which allogeneic bone marrow… CONTINUE READING
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Harmonized testing for BCR-ABL kinase domain mutations in CML: results of a survey and first control round within 28 national laboratories in Europe [Abstract

  • T Ernst, F Lin, EH White
  • 52nd ASH Annual Meeting and Exposition
  • 2010
1 Excerpt

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