Laboratory to Community: Chemoprevention Is the Answer

@article{Olden2014LaboratoryTC,
  title={Laboratory to Community: Chemoprevention Is the Answer},
  author={K. Olden and S. V. Vulimiri},
  journal={Cancer Prevention Research},
  year={2014},
  volume={7},
  pages={648 - 652}
}
  • K. Olden, S. V. Vulimiri
  • Published 2014
  • Medicine
  • Cancer Prevention Research
  • In the current issue, Johnson and colleagues present exciting results, using biomarkers involved in aflatoxin B1 (AFB1)–induced hepatocarcinogenesis, as an example of a conceptual framework to target mechanisms of action in developing chemopreventive agents. Their innovative approach offers considerable promise for a field that has long been neglected. Proof-of-principle was demonstrated using a synthetic triterpenoid (CDDO-Im), which activates Nrf2 signal transduction pathway, inhibits… CONTINUE READING
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