Laboratory markers for over-attenuation of mumps vaccine virus.

@article{YuS1988LaboratoryMF,
  title={Laboratory markers for over-attenuation of mumps vaccine virus.},
  author={Boriskin YuS and T. Kaptsova and V. Lotte and O. I. Skvortsova and C. Orvell},
  journal={Vaccine},
  year={1988},
  volume={6 6},
  pages={
          483-8
        }
}
The properties of mumps vaccine virus (Leningrad-3 strain) gradually changed upon passaging in quail embryo fibroblasts, the substrate normally used for mumps vaccine production in the USSR. Alterations were extremely noticeable in the over-attenuated (38th passage) virus variant, and involved (a) poor, if any, antibody response in guinea-pigs, (b) turbid plaque formation, (c) lack of expression in cell culture of fusion protein and reduced expression of polymerase protein, and (d) enrichment… Expand
Role of Microparticles in Dengue Virus Infection and Its Impact on Medical Intervention Strategies
Rapid detection of mumps virus by the polymerase chain reaction.
Mumpsimpfstoffe: Virologische Grundlagen
...
1
2
...

References

SHOWING 1-10 OF 11 REFERENCES
The reactions of monoclonal antibodies with structural proteins of mumps virus.
  • C. Orvell
  • Biology, Medicine
  • Journal of immunology
  • 1984
Live, attenuated mumps-virus vaccine.
...
1
2
...