Laboratory evaluation of the antiphospholipid syndrome.

  title={Laboratory evaluation of the antiphospholipid syndrome.},
  author={Stephen M. Abo and Vincent A. Debari},
  journal={Annals of clinical and laboratory science},
  volume={37 1},
The antiphospholipid syndrome (APS) was first described in 1986. The original association of this hypercoagulable state with anticardiolipin antibodies (aCL) resulted from the synthesis of evidence stemming from laboratory findings in systemic lupus erythematosus (SLE), ie, the frequent occurrence of false-positive VDRL tests and the paradoxical observation of the so-called "lupus anticoagulant" (LA), an increase in phospholipid (PL)-dependent clotting times. By the early 1990s, it was clear… CONTINUE READING


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