Laboratory diagnosis of legionnaires' disease due to Legionella pneumophila serogroup 1: comparison of phenotypic and genotypic methods.

@article{Lindsay2004LaboratoryDO,
  title={Laboratory diagnosis of legionnaires' disease due to Legionella pneumophila serogroup 1: comparison of phenotypic and genotypic methods.},
  author={Diane S. J. Lindsay and William H Abraham and William A Findlay and Peter Christie and Fiona Johnston and Giles F. S. Edwards},
  journal={Journal of medical microbiology},
  year={2004},
  volume={53 Pt 3},
  pages={183-7}
}
Laboratory results of 67 cases of legionnaires' disease caused by Legionella pneumophila serogroup (Sg) 1 spanning a 6-year period were analysed by both phenotypic and genotypic methods. The methods compared were urinary antigen enzyme immunoassay (EIA), an immunofluorescent antibody (IFA) test, direct fluorescent antibody (DFA), culture and a 5S rRNA PCR with Southern blotting confirmation. Urine was available in 53 cases, of which 35 (66%) were positive, with an antigen peak observed at 5-10… CONTINUE READING

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