Laboratory diagnosis of herpes zoster.

  title={Laboratory diagnosis of herpes zoster.},
  author={Andreas Sauerbrei and Ulrich Eichhorn and Michael Schacke and Peter Wutzler},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  volume={14 1},
Virological diagnosis of zoster should be rapid when effective antiviral chemotherapy is being considered. In the present study, vesicle specimens of 100 patients with zoster were analysed by detecting viral DNA using polymerase chain reaction (PCR). The findings were compared with those obtained by traditional virological and serological methods. PCR results confirmed the clinical diagnosis of zoster in 95%. Primers selected from varicella-zoster virus (VZV) gene 28 proved to be most sensitive… CONTINUE READING
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