Laboratory diagnosis of central nervous system infections caused by herpesviruses.

  title={Laboratory diagnosis of central nervous system infections caused by herpesviruses.},
  author={Andreas Sauerbrei and Peter Wutzler},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  volume={25 Suppl 1},
BACKGROUND Herpesviruses may be associated with various types of central nervous system (CNS) infections. Herpes simplex encephalitis (HSE) has to be considered one of the most severe diseases. As effective antiviral drugs are available, rapid and reliable diagnosis has become important. OBJECTIVES To describe polymerase chain reaction (PCR) and serological methods for the detection of herpesvirus-induced CNS infections by the example of HSE. STUDY DESIGN 620 cerebrospinal fluid (CSF) and… CONTINUE READING


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