Laboratory diagnosis of Clostridium difficile disease.

  title={Laboratory diagnosis of Clostridium difficile disease.},
  author={Michel Delm{\'e}e},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  volume={7 8},
  • Michel Delmée
  • Published 2001 in
    Clinical microbiology and infection : the…
The laboratory diagnosis of Clostridium difficile-associated disease (CDAD) is based on culture and toxin detection in fecal specimens. Culture is performed on a commercially available selective media. C. difficile colony morphology is typical when viewed under a dissecting microscope. Definitive identification is best obtained by gas liquid chromatography. Culture is very sensitive but, when used alone without toxin testing, it leads to low specificity and misdiagnosis of CDAD when high rates… CONTINUE READING


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