Laboratory diagnosis and interpretation of tests for syphilis.

  title={Laboratory diagnosis and interpretation of tests for syphilis.},
  author={Stine Anna Larsen and Bret M. Steiner and Annette Rudolph},
  journal={Clinical microbiology reviews},
  volume={8 1},
The lack of a method for demonstrating the presence of Treponema pallidum by growth necessitates the use of alternative methods. Traditionally, these methods are divided into direct detection methods (animal inoculation, dark-field microscopy, etc.) and serologic tests for the presence of patient antibody against T. pallidum. Serologic methods are further divided into two classes. One class, the nontreponemal tests, detects antibodies to lipoidal antigens present in either the host or T… CONTINUE READING
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