Laboratory data which differentiate meropenem and imipenem.

@article{Edwards1995LaboratoryDW,
  title={Laboratory data which differentiate meropenem and imipenem.},
  author={Jeffrey R. Edwards and Philip J. Turner},
  journal={Scandinavian journal of infectious diseases. Supplementum},
  year={1995},
  volume={96},
  pages={5-10}
}
Meropenem and imipenem are carbapenems which are distinguishable from all other currently available beta-lactam antibiotics by breadth of antibacterial spectrum and stability to beta-lactamases, but can be differentiated one from another. Meropenem is relatively stable to human renal dehydropeptidase-I (DHP-I); it does not require to be co-administered with cilastatin and consequently, unlike imipenem, will be administered as a single agent. In vitro both meropenem and imipenem are active… CONTINUE READING
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