Laboratory assessment of vitamin K status

  title={Laboratory assessment of vitamin K status},
  author={D. Card and R. G{\'o}rska and D. Harrington},
  journal={Journal of Clinical Pathology},
  pages={70 - 75}
  • D. Card, R. Górska, D. Harrington
  • Published 2019
  • Medicine
  • Journal of Clinical Pathology
  • Vitamin K is required for the ɣ-carboxylation of specific glutamic acid residues within the Gla domain of the 17 vitamin K-dependent proteins (VKDPs). The timely detection and correction of vitamin K deficiency can protect against bleeding. Vitamin K also plays a role in bone metabolism and vascular calcification. Patients at increased risk of vitamin K deficiency include those with a restricted diet or malnutrition, lipid malabsorption, cancer, renal disease, neonates and the elderly… CONTINUE READING
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