Laboratory aspects in the diagnosis of coccidioidomycosis.

  title={Laboratory aspects in the diagnosis of coccidioidomycosis.},
  author={Michael A. Saubolle},
  journal={Annals of the New York Academy of Sciences},
Coccidioides immitis and Coccidioides posadasii, the two recognized causes of coccidioidomycosis, may be detected by direct microscopy, culture, and serologic documentation. Two useful stains include the Grocott methenamine silver (GMS) and the calcofluor white (CFW). Other useful stains used in histopathologic studies include hematoxylin-eosin (H&E) and periodic acid Schiff (PAS). Nucleic acid amplification tests (NAATs) have been introduced for detection of Coccidioides spp. in specimens, but… CONTINUE READING


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